#ReversePhysiology: What Is Diabetes?
Nigeria
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✒️ - By Aan Gray
Diabetes is any metabolic disorder resulting in chronic polyuria. There are at least four forms of diabetes:
• Diabetes mellitus Type 1,
• Diabetes mellitus Type 2,
• Gestational diabetes, and
• Diabetes insipidus.
In most cases, the polyuria results from a high concentration of glucose in the renal tubule. Glucose osmotically retains water in the tubule, so more water passes in the urine (osmotic diuresis) and a person may become severely dehydrated. In diabetes mellitus and gestational diabetes, the high glucose level in the tubular fluid is a result of hyperglycemia, a high level in the blood.
About 1% to 3% of pregnant women experience gestational diabetes, in which pregnancy reduces the mother's insulin sensitivity, resulting in hyperglycemia and glycosuria. Diabetes insipidus results from ADH hyposecretion. Without ADH, the collecting duct does not reabsorb much water, so more water passes in the urine. Diabetes mellitus and gestational diabetes are characterized by glycosuria. Before chemical tests for urine glucose were developed, physicians diagnosed diabetes mellitus by tasting the patient's urine for sweetness.
Tests for glycosuria are now as simple as dipping a chemical test strip into the urine specimen — an advance in medical technology for which urologists are no doubt grateful. In diabetes insipidus, the urine contains no glucose and, by the old diagnostic method, would not taste sweet.
The old method was one heck of a way to diagnosis! [0x1f602]
Tags: #ScienceWithGray #ScienceOnBuzz #HealthyLifeMatters #Science
Diabetes is any metabolic disorder resulting in chronic polyuria. There are at least four forms of diabetes:
• Diabetes mellitus Type 1,
• Diabetes mellitus Type 2,
• Gestational diabetes, and
• Diabetes insipidus.
In most cases, the polyuria results from a high concentration of glucose in the renal tubule. Glucose osmotically retains water in the tubule, so more water passes in the urine (osmotic diuresis) and a person may become severely dehydrated. In diabetes mellitus and gestational diabetes, the high glucose level in the tubular fluid is a result of hyperglycemia, a high level in the blood.
About 1% to 3% of pregnant women experience gestational diabetes, in which pregnancy reduces the mother's insulin sensitivity, resulting in hyperglycemia and glycosuria. Diabetes insipidus results from ADH hyposecretion. Without ADH, the collecting duct does not reabsorb much water, so more water passes in the urine. Diabetes mellitus and gestational diabetes are characterized by glycosuria. Before chemical tests for urine glucose were developed, physicians diagnosed diabetes mellitus by tasting the patient's urine for sweetness.
Tests for glycosuria are now as simple as dipping a chemical test strip into the urine specimen — an advance in medical technology for which urologists are no doubt grateful. In diabetes insipidus, the urine contains no glucose and, by the old diagnostic method, would not taste sweet.
The old method was one heck of a way to diagnosis! [0x1f602]
Tags: #ScienceWithGray #ScienceOnBuzz #HealthyLifeMatters #Science
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